The Glycogen Synthase Kinase 3α and β Isoforms Differentially Regulates Interleukin-12p40 Expression in Endothelial Cells Stimulated with Peptidoglycan from Staphylococcus aureus

@inproceedings{CortsVieyra2015TheGS,
  title={The Glycogen Synthase Kinase 3α and β Isoforms Differentially Regulates Interleukin-12p40 Expression in Endothelial Cells Stimulated with Peptidoglycan from Staphylococcus aureus},
  author={Ricarda Cort{\'e}s-Vieyra and Octavio Silva-Garc{\'i}a and Javier Oviedo-Boyso and Alejandro Huante-Mendoza and Alejandro Bravo-Pati{\~n}o and Juan Jos{\'e} Valdez-Alarc{\'o}n and Brett B. Finlay and V{\'i}ctor M Baizabal-Aguirre and Yi-Hsien Hsieh},
  booktitle={PloS one},
  year={2015}
}
Glycogen synthase kinase 3 (GSK3) is a constitutively active regulatory enzyme that is important in cancer, diabetes, and cardiovascular, neurodegenerative, and psychiatric diseases. While GSK3α is usually important in neurodegenerative and psychiatric diseases GSK3β is fundamental in the inflammatory response caused by bacterial components. Peptidoglycan… CONTINUE READING