The Gluten-Free/Casein-Free Diet: A Double-Blind Challenge Trial in Children with Autism

@article{Hyman2016TheGD,
  title={The Gluten-Free/Casein-Free Diet: A Double-Blind Challenge Trial in Children with Autism},
  author={Susan L. Hyman and Patricia A. Stewart and Jennifer Foley and Usa Cain and Robin Peck and Danielle D. Morris and Hongyue Wang and Tristram H. Smith},
  journal={Journal of Autism and Developmental Disorders},
  year={2016},
  volume={46},
  pages={205-220}
}
Key MethodAbstract To obtain information on the safety and efficacy of the gluten-free/casein-free (GFCF) diet, we placed 14 children with autism, age 3–5 years, on the diet for 4–6 weeks and then conducted a double-blind, placebo-controlled challenge study for 12 weeks while continuing the diet, with a 12-week follow-up. Dietary challenges were delivered via weekly snacks that contained gluten, casein, gluten and casein, or placebo. With nutritional counseling, the diet was safe and well-tolerated…

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