The Global Transcriptional Response of Escherichia coli to Induced 32 Protein Involves 32 Regulon Activation Followed by Inactivation and Degradation of 32 in Vivo *

@inproceedings{Zhao2005TheGT,
  title={The Global Transcriptional Response of Escherichia coli to Induced 32 Protein Involves 32 Regulon Activation Followed by Inactivation and Degradation of 32 in Vivo *},
  author={Kai Zhao and Mingzhu Liu and R. R. Burgess},
  year={2005}
}
32 is the first alternative factor discovered in Escherichia coli and can direct transcription of many genes in response to heat shock stress. To define the physiological role of , we have used transcription profiling experiments to identify, on a genome-wide basis, genes under the control of 32 in E. coli by moderate induction of a plasmid-borne rpoH gene under defined, steadystate growth conditions. Together with a bioinformatics approach, we successfully confirmed genes known previously to… CONTINUE READING