The Genotype and Expression of the TGFβ2 Gene in Children With Congenital Conotruncal Defects

Abstract

Animal studies have shown that knockout of the transforming growth factor beta-2 (TGFβ2) gene results in diverse cardiovascular malformations and that its unregulated expression is involved in the pathogenesis of heart defects. However, little information is available on the genetic and expression alternations of the TGFβ2 gene in children with congenital… (More)
DOI: 10.1007/s00246-013-0696-2

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