The Genotype-Tissue Expression (GTEx) project

@article{Lonsdale2013TheGE,
  title={The Genotype-Tissue Expression (GTEx) project},
  author={John T. Lonsdale and Jeffrey A. Thomas and Mike Salvatore and Rebecca Phillips and Edmund Lo and Saboor Shad and Richard Hasz and Gary D. Walters and Fernando Garc{\'i}a and Nancy Young and Barbara Foster and Mike Moser and Ellen Karasik and Bryan M. Gillard and Kimberley Ramsey and Susan Buhr Sullivan and Jason P. Bridge and Harold Magazine and John Syron and Johnelle Fleming and Laura A. Siminoff and Heather M. Traino and Maghboeba Mosavel and Laura Barker and Scott Jewell and Dan Rohrer and Dan Maxim and Dana Filkins and Philip R. Harbach and Eddie Cortadillo and Bree D Berghuis and Lisa Pedersen Turner and Eric Hudson and Kristin Feenstra and Leslie H. Sobin and James Robb and Phillip Branton and Greg E. Korzeniewski and Charles Shive and David C. Tabor and Liqun Qi and Kevin Groch and Sreenath Nampally and Steve Buia and Angela Zimmerman and Anna Deavere Smith and Robin Burges and Karna L. Robinson and Kim Valentino and Deborah Bradbury and Mark Cosentino and Norma Diaz-Mayoral and Mary Kennedy and Theresa Engel and Penelope Williams and Kenyon Erickson and Kristin G. Ardlie and Wendy Winckler and Gad Getz and David S. DeLuca and Daniel MacArthur and Manolis Kellis and Alexander Thomson and Taylor T. Young and Ellen T. Gelfand and Molly Donovan and Yan Shuang Meng and George Grant and Deborah C. Mash and Yvonne Marcus and Margaret R. Basile and Jun S. Liu and Jun Zhu and Zhidong Tu and Nancy J. Cox and Dan L. Nicolae and Eric R. Gamazon and Hae Kyung Im and Anuar Konkashbaev and Jonathan K. Pritchard and Matthew Stevens and Timoth{\'e}e Flutre and Xiaoquan Wen and Emmanouil T. Dermitzakis and Tuuli Lappalainen and Roderic Guig{\'o} and Jean Monlong and Michael Sammeth and Daphne Koller and Alexis Battle and Sara Mostafavi and Mark Mccarthy and Manuel A. Rivas and Julian B. Maller and Ivan Rusyn and Andrew B. Nobel and Fred Wright and Andrey A. Shabalin and Mike Feolo and Nataliya Sharopova and Anne Sturcke and Justin Paschal and James Melvin Anderson and Elizabeth L. Wilder and Leslie K. Derr and Eric D. Green and Jeffery P. Struewing and Gary F. Temple and Simona Volpi and Joy T Boyer and Elizabeth J. Thomson and M. Susan Guyer and Cathy Ng and Assya Abdallah and Deborah Colantuoni and Thomas R. Insel and Susan E. Koester and Alvin R. Little and Patrick K Bender and Thomas Lehner and Yin Yao and Carolyn C. Compton and Jimmie B. Vaught and Sherilyn J Sawyer and Nicole C. Lockhart and Joanne P. Demchok and Helen Moore},
  journal={Nature Genetics},
  year={2013},
  volume={45},
  pages={580-585}
}
Genome-wide association studies have identified thousands of loci for common diseases, but, for the majority of these, the mechanisms underlying disease susceptibility remain unknown. Most associated variants are not correlated with protein-coding changes, suggesting that polymorphisms in regulatory regions probably contribute to many disease phenotypes. Here we describe the Genotype-Tissue Expression (GTEx) project, which will establish a resource database and associated tissue bank for the… CONTINUE READING

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