The Genomic HyperBrowser: inferential genomics at the sequence level

  title={The Genomic HyperBrowser: inferential genomics at the sequence level},
  author={Geir Kjetil Sandve and Sveinung Gundersen and Halfdan Rydbeck and Ingrid Kristine Glad and Lars Holden and Marit Holden and Knut Liest{\o}l and Trevor Clancy and Egil Ferkingstad and Morten Johansen and Vegard Nygaard and Eivind T{\o}stesen and Arnoldo Frigessi and Eivind Hovig},
  journal={Genome Biology},
  pages={R121 - R121}
The immense increase in the generation of genomic scale data poses an unmet analytical challenge, due to a lack of established methodology with the required flexibility and power. We propose a first principled approach to statistical analysis of sequence-level genomic information. We provide a growing collection of generic biological investigations that query pairwise relations between tracks, represented as mathematical objects, along the genome. The Genomic HyperBrowser implements the… 

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