The Genomic Formation of South and Central Asia

  title={The Genomic Formation of South and Central Asia},
  author={Vagheesh M. Narasimhan and Nick J. Patterson and Priya Moorjani and Iosif Lazaridis and Mark Lipson and Swapan Mallick and Nadin Rohland and Rebecca Bernardos and Alexander M. Kim and Nathan Nakatsuka and I{\~n}igo Olalde and Alfredo Coppa and James P. Mallory and Vyacheslav Moiseyev and Janet M Monge and Luca M. Olivieri and Nicole Adamski and Nasreen Broomandkhoshbacht and Francesca Candilio and Olivia Cheronet and Brendan J Culleton and Matthew Ferry and Daniel M. Fernandes and Beatriz Gamarra and Daniel Gaudio and Mateja Hajdinjak and {\'E}adaoin Harney and Thomas K. Harper and Denise Keating and Ann Marie Lawson and Megan Michel and Mario Novak and Jonas Oppenheimer and Niraj Rai and Kendra A. Sirak and Viviane Slon and Kristin Stewardson and Zhao Zhang and Gaziz Akhatov and Anatoly N Bagashev and Bauryzhan Baitanayev and Gianluca Bonora and Tatiana Chikisheva and Anatoly P. Derevianko and Enshin Dmitry and Katerina Douka and Nadezhda Dubova and Andrey V. Epimakhov and Suzanne Freilich and Dorian Q. Fuller and Alexander Goryachev and Andrey Gromov and Bryan Hanks and Margaret A. Judd and Erlan Kazizov and Aleksander Khokhlov and Egor Kitov and Elena V. Kupriyanova and Pavel Kuznetsov and Donata Luiselli and Farhod Maksudov and Christopher Meiklejohn and Deborah C. Merrett and Roberto Micheli and Oleg Dmitrievich Mochalov and Zahir Muhammed and Samariddin Mustafokulov and Ayushi Nayak and Rykun M Petrovna and Davide Pettener and Richard Potts and Dmitry I. Razhev and Stefania Sarno and Kulyan Sikhymbaeva and Sergey Slepchenko and Nadezhda Stepanova and Svetlana V Svyatko and Sergey Vasilyev and Massimo Vidale and Dmitriy Voyakin and Antonina Yermolayeva and Alisa V. Zubova and Vasant S. Shinde and Carles Lalueza-Fox and Matthias Meyer and David Anthony and Nicole Boivin and Kumarasamy Thangaraj and Douglas J. Kennett and Michael Frachetti and Ron Pinhasi and David Reich},
The genetic formation of Central and South Asian populations has been unclear because of an absence of ancient DNA. [] Key Result We document a southward spread of genetic ancestry from the Eurasian Steppe, correlating with the archaeologically known expansion of pastoralist sites from the Steppe to Turan in the Middle Bronze Age (2300-1500 BCE).

The formation of human populations in South and Central Asia

It is shown that Steppe ancestry then integrated further south in the first half of the second millennium BCE, contributing up to 30% of the ancestry of modern groups in South Asia, supporting the idea that the archaeologically documented dispersal of domesticates was accompanied by the spread of people from multiple centers of domestication.

Ancient human genome-wide data from a 3000-year interval in the Caucasus corresponds with eco-geographic regions

The authors generate genome-wide SNP data for 45 Eneolithic and Bronze Age individuals across the Caucasus, and find distinct genetic clusters between mountain and steppe zones as well as occasional gene-flow.

The genetic history of admixture across inner Eurasia

Genome-wide data for 763 individuals from inner Eurasia reveal 3 admixture clines in present-day populations that mirror geography, illuminating the historic spread and mixture of peoples across the Eurasian steppe, taiga and tundra.

The genetic makings of South Asia.

Characterizing the genetic history of admixture across inner Eurasia

The genetic structure of Caucasus populations highlights a role of the Caucasus Mountains as a barrier to gene flow and suggests a post-Neolithic gene flow into North Caucasus populations from the steppe.

The genetic prehistory of the Greater Caucasus

The steppe groups from Yamnaya and subsequent pastoralist cultures show evidence for previously undetected farmer-related ancestry from different contact zones, while Steppe Maykop individuals harbour additional Upper Palaeolithic Siberian and Native American related ancestry.

The Genetic Ancestry of Modern Indus Valley Populations from Northwest India.

On Peopling of India: Ancient DNA perspectives By K Thangaraj and

The authors here extensively described the aDNA studies initiated and completed in India and suggested that a South Asian hunter-gatherer lineage with close genetic proximity to the present-day Andamanese people (AASI) admixed with Iranian agriculturists approximately in the 3rd millennium BCE and was suggested that this gene pool was the major source of the subsequent peopling of the Indian subcontinent.

Historic migration to South Asia in the last two millennia: A case of Jewish and Parsi populations

In this study, a broad genetic profile of Indian Jews and Parsis is reconstructed to paint a fine-grained picture of these ethnic groups.

Historic migration to South Asia in the last two millennia: A case of Jewish and Parsi populations

The South Asian populations have a mosaic of ancestries likely due to the interactions of long-term populations of the landmass and those of East and West Eurasia. Apart from prehistoric dispersals,



The Genomic History of Southeastern Europe

It is shown that southeastern Europe continued to be a nexus between east and west after the arrival of farmers, with intermittent genetic contact with steppe populations occurring up to 2,000 years earlier than the migrations from the steppe that ultimately replaced much of the population of northern Europe.

Genomic insights into the origin of farming in the ancient Near East

We report genome-wide ancient DNA from 44 ancient Near Easterners ranging in time between ~12,000 and 1,400 bc, from Natufian hunter–gatherers to Bronze Age farmers. We show that the earliest

Early Neolithic genomes from the eastern Fertile Crescent

It is concluded that multiple, genetically differentiated hunter-gatherer populations adopted farming in southwestern Asia, that components of pre-Neolithic population structure were preserved as farming spread into neighboring regions, and that the Zagros region was the cradle of eastward expansion.

The genetics of an early Neolithic pastoralist from the Zagros, Iran

It is shown that Western Iran was inhabited by a population genetically most similar to hunter-gatherers from the Caucasus, but distinct from the Neolithic Anatolian people who later brought food production into Europe.

Upper Palaeolithic Siberian genome reveals dual ancestry of Native Americans

The findings reveal that western Eurasian genetic signatures in modern-day Native Americans derive not only from post-Columbian admixture, as commonly thought, but also from a mixed ancestry of the First Americans.

Reconstructing Indian Population History

It is predicted that there will be an excess of recessive diseases in India, which should be possible to screen and map genetically and is higher in traditionally upper caste and Indo-European speakers.

Ancestry and demography and descendants of Iron Age nomads of the Eurasian Steppe

Genomic inference reveals that Scythians in the east and the west of the steppe zone can best be described as a mixture of Yamnaya-related ancestry and an East Asian component, and finds evidence that significant gene-flow from east to west Eurasia must have occurred early during the Iron Age.

The Beaker Phenomenon and the Genomic Transformation of Northwest Europe

Genome-wide data from 400 Neolithic, Copper Age and Bronze Age Europeans is presented, finding limited genetic affinity between Beaker-complex-associated individuals from Iberia and central Europe, and excludes migration as an important mechanism of spread between these two regions.

An early modern human from Romania with a recent Neanderthal ancestor

DNA from a 37,000–42,000-year-old modern human from Peştera cu Oase, Romania is analysed, finding that on the order of 6–9% of the genome of the Oase individual is derived from Neanderthals, more than any other modern human sequenced to date.

Genetic evidence for recent population mixture in India.