The Genome of the Natural Genetic Engineer Agrobacterium tumefaciens C58

  title={The Genome of the Natural Genetic Engineer Agrobacterium tumefaciens C58},
  author={D. W. Wood and J. Setubal and R. Kaul and D. E. Monks and J. P. Kitajima and V. Okura and Y. Zhou and L. Chen and G. Wood and N. Almeida and L. Woo and Y. Chen and I. Paulsen and J. Eisen and P. Karp and D. Bovee and P. Chapman and J. Clendenning and G. Deatherage and W. Gillet and C. Grant and T. Kutyavin and R. Levy and M. J. Li and E. McClelland and A. Palmieri and C. Raymond and G. Rouse and C. Saenphimmachak and Z. Wu and P. Romero and D. Gordon and S. Zhang and H. Yoo and Y. Tao and P. Biddle and M. Jung and W. Krespan and M. Perry and B. Gordon-Kamm and L. Liao and S. Kim and C. Hendrick and Z. Zhao and M. Dolan and F. Chumley and S. Tingey and J. Tomb and M. Gordon and M. Olson and E. Nester},
  pages={2317 - 2323}
  • D. W. Wood, J. Setubal, +48 authors E. Nester
  • Published 2001
  • Biology, Medicine
  • Science
  • The 5.67-megabase genome of the plant pathogen Agrobacterium tumefaciens C58 consists of a circular chromosome, a linear chromosome, and two plasmids. Extensive orthology and nucleotide colinearity between the genomes of A. tumefaciens and the plant symbiont Sinorhizobium meliloti suggest a recent evolutionary divergence. Their similarities include metabolic, transport, and regulatory systems that promote survival in the highly competitive rhizosphere; differences are apparent in their genome… CONTINUE READING
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    We thank P. Green for useful discussions, R. Gibson for providing the genome_plot program, and J. Staley for critical review of the manuscript
    • NIH Public Health Service grant GM32618 (E.W.N.), NIH doctoral fellowship GM19642 (D.W.W.), Sao Paulo State Research Foundation (FAPESP) sabbatical fellowship 1999/11876-5 ( J.C.S.), a FUNDECT-MS grant (N.F.A.), and the E. I. du Pont de Nemours Company
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