The Genome of the African Trypanosome

@inproceedings{Donelson2002TheGO,
  title={The Genome of the African Trypanosome},
  author={J. Donelson},
  year={2002}
}
Trypanosoma brucei is a diploid organism with a nuclear haploid DNA content of 35 ± 9 megabase pairs (Mb) depending on the trypanosome isolate. About 15% of the total cellular DNA is in the kinetoplast where it is organized as homogenous 23-kb maxicircles and heterogeneous 1 -kb minicircles. The remaining 85% of the DNA occurs in the nucleus as linear DNA molecules ranging in size from 50 kb to 6 Mb. At least 11 pairs of megabase chromosomes of 1 to 6 Mb exist that are numbered I-XI from… Expand
Hemizygous subtelomeres of an African trypanosome chromosome may account for over 75% of chromosome length.
TLDR
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  • Biology, Medicine
  • Essays in biochemistry
  • 2010
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TLDR
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