The Genome Sequence of the SARS-Associated Coronavirus

  title={The Genome Sequence of the SARS-Associated Coronavirus},
  author={M. Marra and S. Jones and C. Astell and R. Holt and A. Brooks-Wilson and Y. Butterfield and J. Khattra and J. Asano and S. Barber and Susanna Y. Chan and A. Cloutier and S. M. Coughlin and D. Freeman and Noreen Girn and O. Griffith and S. Leach and Michael Mayo and H. McDonald and S. Montgomery and P. Pandoh and Anca S. Petrescu and A. G. Robertson and J. Schein and A. Siddiqui and D. Smailus and J. Stott and G. Yang and F. Plummer and A. Andonov and H. Artsob and N. Bastien and K. Bernard and T. Booth and D. Bowness and M. Czub and M. Drebot and Lisa Fernando and Ramon Flick and Michael Garbutt and Michael Gray and A. Grolla and H. Feldmann and A. Meyers and Amin Kabani and Y. Li and Susan Normand and Ute Stroher and G. Tipples and S. Tyler and Robert Vogrig and D. Ward and B. Watson and R. Brunham and M. Krajden and M. Petric and D. Skowronski and C. Upton and R. Roper},
  pages={1399 - 1404}
  • M. Marra, S. Jones, +56 authors R. Roper
  • Published 2003
  • Biology, Medicine
  • Science
  • We sequenced the 29,751-base genome of the severe acute respiratory syndrome (SARS)–associated coronavirus known as the Tor2 isolate. The genome sequence reveals that this coronavirus is only moderately related to other known coronaviruses, including two human coronaviruses, HCoV-OC43 and HCoV-229E. Phylogenetic analysis of the predicted viral proteins indicates that the virus does not closely resemble any of the three previously known groups of coronaviruses. The genome sequence will aid in… CONTINUE READING
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