The Genome Organization of the Nidovirales: Similarities and Differences between Arteri-, Toro-, and Coronaviruses☆

  title={The Genome Organization of the Nidovirales: Similarities and Differences between Arteri-, Toro-, and Coronaviruses☆},
  author={Antoine A. F. de Vries and Marian C. Horzinek and Peter J. M. Rottier and Raoul J. de Groot},
  journal={Seminars in Virology},
  pages={33 - 47}
Abstract Viruses in the families Arteriviridae and Coronaviridae have enveloped virions which contain nonsegmented, positive-stranded RNA, but the constituent genera differ markedly in genetic complexity and virion structure. Nevertheless, there are striking resemblances among the viruses in the organization and expression of their genomes, and sequence conservation among the polymerase polyproteins strongly suggests that they have a common ancestry. On this basis, the International… 

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