The Genetics of Signal Transduction and the Feto-Maternal Relationship. A Study of Cytosolic Low Molecular Weight Phosphotyrosine Phosphatase

Abstract

Intracellular kinases mediate positive signalling from surface receptors by phosphorylating critical target proteins whereas phosphatases inhibit this process. Differential phosphatase activity at the feto-maternal interface could determine the appropriate relative growth and development on each side of the placenta. The highly polymorphic cytosolic low… (More)

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