The Genetics of Primary Microcephaly.

  title={The Genetics of Primary Microcephaly.},
  author={Divya Jayaraman and Byoung-il Bae and Christopher A. Walsh},
  journal={Annual review of genomics and human genetics},
Primary microcephaly (MCPH, for "microcephaly primary hereditary") is a disorder of brain development that results in a head circumference more than 3 standard deviations below the mean for age and gender. It has a wide variety of causes, including toxic exposures, in utero infections, and metabolic conditions. While the genetic microcephaly syndromes are relatively rare, studying these syndromes can reveal molecular mechanisms that are critical in the regulation of neural progenitor cells… 

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