The Genetic Basis of Lateralization

  title={The Genetic Basis of Lateralization},
  author={Marian Annett},
This is the author's final draft of the paper published as Chapter 5 of : Language lateralization and psychosis / edited by Iris E.C. Sommer, Rene S. Kahn - Cambridge : Cambridge University Press, 2009. It appears here with the permission of the publisher and the editor. The final version is available from 
Correction: Can Population-Level Laterality Stem from Social Pressures? Evidence from Cheek Kissing in Humans
This research presents a novel probabilistic procedure that allows for direct measurement of the response of the immune system to earthquake-triggered landsliding.
Structural connectivity in the asymmetric brain: Genetic and nongenetic influences
ii Acknowledgments iv List of Publications v List of Tables viii List of Figures ix List of Abbreviations xi Chapter 1: General introduction 1 Hemispheric specialization 1 Origins of hemispheric
Asymmetries of the Arcuate Fasciculus in Monozygotic Twins: Genetic and Nongenetic Influences
Reversals of arcuate fasciculus asymmetry were restricted to pairs discordant for language dominance, with the left-cerebrally dominant twins showing leftward and the right-ceretarily dominant twins rightward asymmetry of anisotropic diffusion in the arcuate Fasciculus.
Can Population-Level Laterality Stem from Social Pressures? Evidence from Cheek Kissing in Humans
Findings show that social pressures are involved in determining laterality, and demonstrate that population-level laterality can stem from social pressures.
The relationship between brain dominance, body laterality and literacy skills in grade 2 learners in a school in KZN
Handedness in Writing
Abstract Handedness is defined as the preference of the hand during the process of writing. The aim here is to report the information gathered from 160 1st year medical students. 13 were left-handed.
The effect of handedness on spatial and motor representation of pitch patterns in pianists
There is a trend of left-handed pianists to be quicker and more accurate in playing melodies when reversing their fingering with reversed contours in their left-hand performances, which suggests that handedness may influence pianists’ skill to adjust to new spatial and motor mappings.
Laterality in the Power Five and Group of Five Conferences in Women's College Softball
Females in sport are under-represented in data and analysis when compared to their male counterparts. This disparity also applies to women’s softball in comparison to men’s baseball. To help fill
Adjustment Errors in Ascending and Descending Phases of Target Level in Controlled Force Exertion
Hand grip force adjustment errors to ascending and descending phases of a sinusoidal target force in a controlled force exertion (CFE) test were measured and the laterality of responses evaluated. 75


Familial aggregation of strong hemispheric language lateralization
A significant familial aggregation of strong left-hemispheric language lateralization and a positive association of the degree of languageateralization between parents and their children were found, which strongly suggest a genetic determination of the level oflanguage lateralization.
Handedness and speech: a critical reappraisal of the role of genetic and environmental factors in the cerebral lateralization of function.
A critical reexamination of the relevant nonhuman and human evidence suggests that although the development of a cerebral lateralization for speech and handedness is dependent on both genetic and environmental factors, the specific role of inborn and postnatal influences is very different.
Schizophrenia Genesis: The Origins of Madness
'The book will appeal to a variety of readers. The history of the illness, its diagnoses, epidemiology, demography, inheritance and environmental stresses would be of general interest. The anguished
Schizophrenia as failure of hemispheric dominance for language.
  • T. Crow
  • Psychology, Medicine
    Trends in neurosciences
  • 1997
Individuals who develop schizophrenic symptoms show lesser anatomical and functional asymmetries than the population as a whole; such symptoms may reflect 'dominance failure' for language.
In Defence of the Right Shift Theory
  • M. Annett
  • Psychology, Medicine
    Perceptual and motor skills
  • 1996
The right shift (RS) theory of a gene for left-cerebral dominance which increases the probability of right-handedness is outlined, together with two proposed alternatives, the 1985a genetic theory of
The distribution of manual asymmetry.
  • M. Annett
  • Psychology, Medicine
    British journal of psychology
  • 1972
It is concluded that the basic normal distribution probably depends on accidental variation while the human shift to the right may be a product of both cultural and genetic influences.
Hand Preference and the Laterality of Cerebral Speech
It is concluded that the evidence is strong enough to offer a useful test of hypotheses as to the distribution of cerebral speech in handedness groups and to justify a reconsideration of the model in the light of the evidence.
A gene-culture model of human handedness
A model of handedness incorporating both genetic and cultural processes is proposed, based on an evolutionary analysis, and maximum-likelihood estimates of its parameters are generated. This model
Handedness, language dominance and aphasia: a genetic model.
  • I. Mcmanus
  • Medicine
    Psychological medicine. Monograph supplement
  • 1985
The same model is fitted, by means of a number of minor conceptual extensions, to data from the literature on the relationship of handedness to language dominance, acute and permanent aphasia, and visual processing dominance.
Schizophrenia and autism considered as the products of an agnosic right shift gene.
  • M. Annett
  • Psychology, Medicine
    Cognitive neuropsychiatry
  • 1997
A mechanism for Crow's theory which requires only one new assumption for the right shift genetic model of handedness and cerebral dominance is suggested, which is that the RS+ allele, whose normal function is to induce the left hemisphere to serve speech by impairing speech-related cortex in the right hemisphere, tends to lose its directional coding.