The Genetic Architecture of the Genome-Wide Transcriptional Response to ER Stress in the Mouse

Abstract

Endoplasmic reticulum (ER) stress occurs when misfolded proteins accumulate in the ER. The cellular response to ER stress involves complex transcriptional and translational changes, important to the survival of the cell. ER stress is a primary cause and a modifier of many human diseases. A first step to understanding how the ER stress response impacts human… (More)
DOI: 10.1371/journal.pgen.1004924

Topics

11 Figures and Tables

Cite this paper

@inproceedings{Chow2015TheGA, title={The Genetic Architecture of the Genome-Wide Transcriptional Response to ER Stress in the Mouse}, author={Clement Y. Chow and Xu Wang and David D. Riccardi and Mariana F Wolfner and Andrew G Clark}, booktitle={PLoS genetics}, year={2015} }