The Genetic Architecture of Degenerin/Epithelial Sodium Channels in Drosophila

@inproceedings{Zelle2013TheGA,
  title={The Genetic Architecture of Degenerin/Epithelial Sodium Channels in Drosophila},
  author={Kathleen M. Zelle and Beika Lu and Sarah C. Pyfrom and Yehuda Ben-Shahar},
  booktitle={G3},
  year={2013}
}
Degenerin/epithelial sodium channels (DEG/ENaC) represent a large family of animal-specific membrane proteins. Although the physiological functions of most family members are not known, some have been shown to act as nonvoltage gated, amiloride-sensitive sodium channels. The DEG/ENaC family is exceptionally large in genomes of Drosophila species relative to vertebrates and other insects. To elucidate the evolutionary history of the DEG/ENaC family in Drosophila, we took advantage of the genomic… CONTINUE READING
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