The Gene Expression Profile in the Synovium as a Predictor of the Clinical Response to Infliximab Treatment in Rheumatoid Arthritis

@inproceedings{Lindberg2010TheGE,
  title={The Gene Expression Profile in the Synovium as a Predictor of the Clinical Response to Infliximab Treatment in Rheumatoid Arthritis},
  author={Johan Lindberg and Carla Ann Wijbrandts and Lisa G. M. van Baarsen and Gustavo Nader and Lars Klareskog and Anca Irinel Catrina and Rogier M. Thurlings and Margriet J.B.M. Vervoordeldonk and Joakim Lundeberg and Paul Peter Tak},
  booktitle={PloS one},
  year={2010}
}
BACKGROUND Although the use of TNF inhibitors has fundamentally changed the way rheumatoid arthritis (RA) is treated, not all patients respond well. It is desirable to facilitate the identification of responding and non-responding patients prior to treatment, not only to avoid unnecessary treatment but also for financial reasons. In this work we have investigated the transcriptional profile of synovial tissue sampled from RA patients before anti-TNF treatment with the aim to identify biomarkers… CONTINUE READING

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