The GTPase Rab3a is associated with large dense core vesicles in bovine chromaffin cells and rat PC12 cells.

@article{Darchen1995TheGR,
  title={The GTPase Rab3a is associated with large dense core vesicles in bovine chromaffin cells and rat PC12 cells.},
  author={François Darchen and Jan Senyshyn and William H. Brondyk and Douglas J Taatjes and Ronald W Holz and J. P. Henry and Jean Pierre Denizot and Ian G. Macara},
  journal={Journal of cell science},
  year={1995},
  volume={108 ( Pt 4)},
  pages={1639-49}
}
Small GTPases of the rab family control intracellular vesicle traffic in eukaryotic cells. Although the molecular mechanisms underlying the activity of the Rab proteins have not been elucidated yet, it is known that the function of these proteins is dependent on their precise subcellular localization. It has been suggested that Rab3a, which is mainly expressed in neural and endocrine cells, might regulate exocytosis. Recently, direct experimental evidence supporting this hypothesis has been… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 14 extracted citations

Divergent functions of neuronal Rab11b in Ca2+-regulated versus constitutive exocytosis.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2003
View 4 Excerpts
Highly Influenced

Calcium-dependent regulation of rab3 in short-term plasticity.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 1998
View 1 Excerpt

Similar Papers

Loading similar papers…