The GTPase-Activating Protein RN-tre Controls Focal Adhesion Turnover and Cell Migration

Abstract

BACKGROUND Integrin-mediated adhesion of cells to the extracellular matrix (ECM) relies on the dynamic formation of focal adhesions (FAs), which are biochemical and mechanosensitive platforms composed of a large variety of cytosolic and transmembrane proteins. During migration, there is a constant turnover of ECM contacts that initially form as nascent… (More)
DOI: 10.1016/j.cub.2013.09.060

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