The GPR17 receptor in NG2 expressing cells: focus on in vivo cell maturation and participation in acute trauma and chronic damage.

@article{Boda2011TheGR,
  title={The GPR17 receptor in NG2 expressing cells: focus on in vivo cell maturation and participation in acute trauma and chronic damage.},
  author={Enrica Boda and Francesca Vigan{\`o} and Patrizia Di Rosa and Marta Fumagalli and Vivien Labat-Gest and Filippo Tempia and Maria P. Abbracchio and Leda Dimou and Annalisa Buffo},
  journal={Glia},
  year={2011},
  volume={59 12},
  pages={1958-73}
}
NG2-expressing cells comprise a population of cycling precursors that can exit the cell cycle and differentiate into mature oligodendrocytes. As a whole, they display heterogeneous properties and behaviors that remain unresolved at the molecular level, although partly interpretable as distinct maturation stages. To address this issue, we analyzed the expression of the GPR17 receptor, recently shown to decorate NG2-expressing cells and to operate as an early sensor of brain damage, in immature… CONTINUE READING

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