The GLH proteins, Caenorhabditis elegans P granule components, associate with CSN-5 and KGB-1, proteins necessary for fertility, and with ZYX-1, a predicted cytoskeletal protein.

@article{Smith2002TheGP,
  title={The GLH proteins, Caenorhabditis elegans P granule components, associate with CSN-5 and KGB-1, proteins necessary for fertility, and with ZYX-1, a predicted cytoskeletal protein.},
  author={Pliny A. Smith and W M Leung-Chiu and Ruth R. Montgomery and April Marie Orsborn and Kathleen Kuznicki and Emily Gressman-Coberly and Lejla Mutap{\vc}i{\'c} and Karen Bennett},
  journal={Developmental biology},
  year={2002},
  volume={251 2},
  pages={
          333-47
        }
}
The GLH proteins belong to a family of four germline RNA helicases in Caenorhabditis elegans. These putative ATP-dependent enzymes localize to the P granules, which are nonmembranous complexes of protein and RNA exclusively found in the cytoplasm of all C. elegans germ cells and germ cell precursors. To determine what proteins the GLHs bind, C. elegans cDNA libraries were screened by the yeast two-hybrid method, using GLHs as bait. Three interacting proteins, CSN-5, KGB-1, and ZYX-1, were… CONTINUE READING

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