The GENCODE pseudogene resource

  title={The GENCODE pseudogene resource},
  author={Baikang Pei and Cristina Sisu and Adam Frankish and C{\'e}dric Howald and Lukas Habegger and Xinmeng Jasmine Mu and Rachel Harte and Suganthi Balasubramanian and Andrea Tanzer and Mark Diekhans and Alexandre Reymond and Tim J. P. Hubbard and Jennifer L. Harrow and Mark B Gerstein},
  booktitle={Genome Biology},
Pseudogenes have long been considered as nonfunctional genomic sequences. However, recent evidence suggests that many of them might have some form of biological activity, and the possibility of functionality has increased interest in their accurate annotation and integration with functional genomics data. As part of the GENCODE annotation of the human genome, we present the first genome-wide pseudogene assignment for protein-coding genes, based on both large-scale manual annotation and in… CONTINUE READING
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