The GDNF family members neurturin, artemin and persephin promote the morphological differentiation of cultured ventral mesencephalic dopaminergic neurons.

@article{Zihlmann2005TheGF,
  title={The GDNF family members neurturin, artemin and persephin promote the morphological differentiation of cultured ventral mesencephalic dopaminergic neurons.},
  author={Karin B Zihlmann and Ang{\'e}lique D. Ducray and Benoit Schaller and Alexander Wilfried Huber and Sandra H Krebs and R H Andres and Rolf W. Seiler and Morten Meyer and Hans Rudolf Widmer},
  journal={Brain research bulletin},
  year={2005},
  volume={68 1-2},
  pages={42-53}
}
Neurturin (NRTN), artemin (ARTN), persephin (PSPN) and glial cell line-derived neurotrophic factor (GDNF) form a group of neurotrophic factors, also known as the GDNF family ligands (GFLs). They signal through a receptor complex composed of a high-affinity ligand binding subunit, postulated ligand specific, and a common membrane-bound tyrosine kinase RET. Recently, also NCAM has been identified as an alternative signaling receptor. GFLs have been reported to promote survival of cultured… CONTINUE READING