The G betagamma dimer as a novel source of selectivity in G-protein signaling: GGL-ing at convention.

@article{Jones2004TheGB,
  title={The G betagamma dimer as a novel source of selectivity in G-protein signaling: GGL-ing at convention.},
  author={Miller B. Jones and David P. Siderovski and Shelley B. Hooks},
  journal={Molecular interventions},
  year={2004},
  volume={4 4},
  pages={200-14}
}
Heterotrimeric G proteins relay information between cell surface receptors and effector molecules in diverse signaling pathways to mediate critical cellular processes in both physiologic and pathologic conditions. Multiple isoforms of each of the three G protein subunits yield enormous structural and functional diversity. G proteins are thus obvious molecular targets for the therapeutic manipulation of signaling pathways. Their ubiquity among a vast array of G protein-coupled receptor pathways… CONTINUE READING

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