The Future Promises of Xenotransplantation a,b

  title={The Future Promises of Xenotransplantation a,b},
  author={Jeffrey L Platt and Shu-sen Lin},
  journal={Annals of the New York Academy of Sciences},
  • J. Platt, Shu-sen Lin
  • Published 1 December 1998
  • Medicine, Biology
  • Annals of the New York Academy of Sciences
ABSTRACT: The use of animals as a source of organs and tissues for humans has been an enduring goal of transplantation. Xenotransplantation, as such, would overcome a shortage of human donors and allow for biochemical or genetic approaches to modification of transplants. The use of animal organs and tissues, however, is hindered by an intense immune response of the recipient against the graft. The molecular basis for this immune response has recently been elucidated, at least in part, and… 

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Effect of Transgenic Expression of Human Decay—Accelerating Factor on the Inhibition of Hyperacute Rejection of Pig Organs

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Mechanism of complement activation in the hyperacute rejection of porcine organs transplanted into primate recipients.

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The role of antibodies in acute vascular rejection of pig-to-baboon cardiac transplants.

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