The Functions of Saliva

@article{Mandel1987TheFO,
  title={The Functions of Saliva},
  author={I. Mandel},
  journal={Journal of Dental Research},
  year={1987},
  volume={66},
  pages={623 - 627}
}
  • I. Mandel
  • Published 1987
  • Biology, Medicine
  • Journal of Dental Research
Nature's demands on salivary glands are extensive and diverse and range from the reptilian need for a venomous drop to incapacitate its prey to the 100 quarts that ruminants require to digest a day's grazing. Other species depend on saliva not for survival, but for improving the quality of life, using the fluid for functions varying from grooming and cleansing to nest-building. Humans can manage without saliva; its loss is not life-threatening in any immediate sense, but it results in a variety… Expand
The significance of saliva during sleep and the relevance of oromotor movements.
TLDR
It is hypothesize herein that lubrication from saliva is necessary during sleep to protect tissue integrity and health of oroesophageal structures. Expand
Salivary mucins in oral mucosal defense.
TLDR
The salivary sulfo- and sialomucins actively participate in the modulation of the oral mucosal calcium channel activity through the inhibition of EGF-stimulated channel protein tyrosine phosphorylation, which is of paramount importance to mucosalcium homeostasis. Expand
In defense of the oral cavity: the protective role of the salivary secretions.
TLDR
This presentation will review recent advances in the genomics and proteomics of saliva, as well as saliva's roles in tissue coating, alimentation, and regulation of the oral flora. Expand
Structural features of salivary function.
  • M. Lamkin, F. Oppenheim
  • Chemistry, Medicine
  • Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists
  • 1993
TLDR
Identifying the functional domains of salivary proteins is vital in understanding the mechanisms of action and this information can be exploited in the development of therapeutic agents. Expand
Sialometria: aspectos de interesse clínico
TLDR
Some aspects related to the role of saliva, the consequences of hyposalivation and methods of salivary flow rate measurement are addressed, useful concepts in the daily practice of rheumatology are addressed. Expand
The use of milk as a saliva substitute.
  • E. L. Herod
  • Medicine
  • Journal of public health dentistry
  • 1994
TLDR
Because of the nutritional, anticariogenic, and moisturizing properties of milk, patients with xerostomia may find milk of value as a saliva substitute to help reduce the oral health problems associated with hyposalivation. Expand
Antibacterial properties of saliva: Role in maternal periparturient grooming and in licking wounds
TLDR
Wound licking, and the application of saliva, would thus reduce wound contamination by E. coli and S. canis, and facilitate the hygienic function of maternal licking of the mammary and anogenital areas in protecting newborns from these diseases. Expand
Release of cariostatic agents from a new buffering fluoride- and xylitol-containing lozenge to human whole saliva in vivo.
TLDR
The results show that the buffering fluoride- and xylitol-containing lozenge, which also releases calcium and phosphate, is active in vivo but its serviceability as a remineralizing agent, in particular for elderly patients with reduced salivary flow rate, has to be analysed separately. Expand
Salivary Gland Secretion
The principal function of mammalian salivary glands is to secrete a protein-rich, watery fluid into the oral cavity. Saliva contains a large repertoire of biologically active molecules thatExpand
Salivary α-Amylase: Role in Dental Plaque and Caries Formation
TLDR
Salivary α-amylase, one of the most plentiful components in human saliva, has at least three distinct biological functions and seems to depend on an intact enzyme conformation. Expand
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 51 REFERENCES
Lipolytic activity of human lingual glands (Ebner).
  • M. Hamosh, W. Burns
  • Biology, Medicine
  • Laboratory investigation; a journal of technical methods and pathology
  • 1977
TLDR
These findings suggest that in man, as previously reported in the rat, the lingual serous glands secrete a lipase that acts in the stomach where it initiates the digestion of dietary fat. Expand
Salivary response to food in humans and its effect on gastric acid secretion.
TLDR
It is suggested that food in the stomach or upper small intestine may activate a reflex or release a hormone into the circulation that augments salivary flow. Expand
Role of salivary mucins in the protection of the oral cavity.
Mucins are the principal organic constituents of mucus, the slimy visco-elastic material that coats all mucosal surfaces. Compelling evidence suggests that they play an integral role in non-immuneExpand
Acid neutralizing capacity of human saliva.
TLDR
Saliva produced at physiologic rates and carried into the esophagus by swallowing is capable of neutralizing small amounts of intraesophageal acid within a few minutes, and the ability of saliva to neutralize acid is due primarily to bicarbonate. Expand
Inhibition of dental plaque acid production by the salivary lactoperoxidase antimicrobial system
Resting human whole saliva inhibited acid production by glucose-stimulated, homologous plaque. The degree of inhibition of plaque acid production correlated positively with the concentration ofExpand
MECHANISM OF SECRETION OF RESTING SALIVA IN MEN.
TLDR
It was verified by experiments with dog that the resting saliva was a reflex saliva, of which receptor stimulation must be a special mechanical stimulus by the attachment of a suction cup, and of which reflex centre was located at the gyrus coronarius, which corresponded to the face area of the anterior central gyrus in human cerebral cortex. Expand
Quantification of granulocyte elastase inhibitors in human mixed saliva and in pure parotid secretion.
TLDR
It is suggested that antileukoproteinase has a biological function in a local defence mechanism directed towards the effects of granulocyte elastase in the oral cavity and salivary glands. Expand
Effect of salivary glands on wound contraction in mice
TLDR
The evidence presented here suggests that contraction is affected by the salivary glands, which is believed to enhance healing by suppressing infection. Expand
Gustin concentration changes relative to salivary zinc and taste in humans.
  • A. Shatzman, R. Henkin
  • Chemistry, Medicine
  • Proceedings of the National Academy of Sciences of the United States of America
  • 1981
TLDR
It is demonstrated that zinc treatment can affect both taste and gustin concentrations in hypogeusia, as well as other protein fractions isolated from patients by column chromatographic techniques. Expand
The Influence of Sialoadenectomy in Rats on Food and Water Consumption
TLDR
In view of several suggestions of deranged metabolic circumstances in sialoadenectomized rats, the food and water consumption of normal and operated rats from a caries-resistant strain and a carie-susceptible strain were studied while they were being maintained on a cariogenic diet. Expand
...
1
2
3
4
5
...