The Functions of Metallothionein and ZIP and ZnT Transporters: An Overview and Perspective.

@article{Kimura2016TheFO,
  title={The Functions of Metallothionein and ZIP and ZnT Transporters: An Overview and Perspective.},
  author={Tomoki Kimura and Taiho Kambe},
  journal={International journal of molecular sciences},
  year={2016},
  volume={17 3},
  pages={
          336
        }
}
Around 3000 proteins are thought to bind zinc in vivo, which corresponds to ~10% of the human proteome. Zinc plays a pivotal role as a structural, catalytic, and signaling component that functions in numerous physiological processes. It is more widely used as a structural element in proteins than any other transition metal ion, is a catalytic component of many enzymes, and acts as a cellular signaling mediator. Thus, it is expected that zinc metabolism and homeostasis have sophisticated… CONTINUE READING

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