The FruA signal transduction protein provides a checkpoint for the temporal co-ordination of intercellular signals in Myxococcus xanthus development.

@article{Ellehauge1998TheFS,
  title={The FruA signal transduction protein provides a checkpoint for the temporal co-ordination of intercellular signals in Myxococcus xanthus development.},
  author={Eva Ellehauge and Mads N\orregaard-Madsen and Lotte S\ogaard-Andersen},
  journal={Molecular microbiology},
  year={1998},
  volume={30 4},
  pages={807-17}
}
During fruiting body morphogenesis in Myxococcus xanthus, the intercellular C-signal induces aggregation, sporulation and developmental gene expression. To understand how a single signal system may induce temporally separated processes, we have focused on the class II gene, which codes for an essential component in the C-signal transduction pathway. We report that class II is identical to fruA and codes for a DNA binding response regulator. Transcription of fruA is developmentally regulated and… CONTINUE READING

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