The Frank--Starling curve.

@article{Noble1978TheFC,
  title={The Frank--Starling curve.},
  author={Mark I M Noble},
  journal={Clinical science and molecular medicine},
  year={1978},
  volume={54 1},
  pages={
          1-7
        }
}
  • M. Noble
  • Published 1978
  • Biology
  • Clinical science and molecular medicine
A basic property of the normal heart is that if its volume is increased, there is an increase in the strength of the contraction. The phenomenon is known as Starling's Law, and as the FrankStarling mechanism. This phenomenon is of great importance. If the heart were unable to increase its output when distended, the distension would become progressively severe. The underlying important relation in the ventri: cular muscle is that between systolic contractile force and muscle (or sarcomere… 

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  • M. Noble
  • Medicine, Biology
    Circulation
  • 1972
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