The Frailty Syndrome: Clinical measurements and basic underpinnings in humans and animals

@article{Mohler2014TheFS,
  title={The Frailty Syndrome: Clinical measurements and basic underpinnings in humans and animals},
  author={Martha Jane Mohler and Mindy Joy Fain and Anne M. Wertheimer and Bijan Najafi and Janko Nikolich-Žugich},
  journal={Experimental Gerontology},
  year={2014},
  volume={54},
  pages={6-13}
}
Frailty is an increasingly recognized syndrome resulting in age-related decline in function and reserve across multiple physiologic systems. It presents as a hyperinflammable state, characterized by high vulnerability for adverse health outcomes, such as disability, falls, hospitalization, institutionalization, and mortality. The prevalence of Frailty Syndrome (FS) is of potentially enormous significance, as it potentially affects 20-30% of adults older than 75. Cellular and molecular basis of… CONTINUE READING

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