The Fluorescence Properties and Lifetime Study of G-quadruplexes Single- and Double-labeled with Pyrene

Abstract

We report steady state fluorescence and lifetime emission studies of d(GGTTGGTGTGGTTGG) (TBA) and d(GGGTTAGGGTTAGGGTTAGGG) (Htelom) oligonucleotides labeled with pyrene through a 3-aminopropyl linker. Such G-rich sequences are able to self-assemble into G-quadruplexes, especially in the presence of specific cations like potassium. A comparative studies with… (More)
DOI: 10.1007/s10895-010-0653-x

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