The Fluid Mosaic Model of the Structure of Cell Membranes

@article{Singer1972TheFM,
  title={The Fluid Mosaic Model of the Structure of Cell Membranes},
  author={S. Singer and G. L. Nicolson},
  journal={Science},
  year={1972},
  volume={175},
  pages={720 - 731}
}
  • S. Singer, G. L. Nicolson
  • Published 1972
  • Chemistry
  • Science
    • A fluid mosaic model is presented for the gross organization and structure of the proteins and lipids of biological membranes. The model is consistent with the restrictions imposed by thermodynamics. In this model, the proteins that are integral to the membrane are a heterogeneous set of globular molecules, each arranged in an amphipathic structure, that is, with the ionic and highly polar groups protruding from the membrane into the aqueous phase, and the nonpolar groups largely buried in the… CONTINUE READING
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