The First Use of Penicillin in the United States

  title={The First Use of Penicillin in the United States},
  author={Charles M. Grossman},
  journal={Annals of Internal Medicine},
  • C. Grossman
  • Published 15 July 2008
  • Medicine
  • Annals of Internal Medicine
The first dose of penicillin given in the United States was administered at YaleNew Haven Hospital on 12 March 1942 to a patient dying of septicemia. As a young Yale house officer, I found myself involved in what few of us then realized was a very profound sequence of events. It was my ninth month of service, and I was an acting assistant resident. On the private floor of the YaleNew Haven Isolation Building, a very ill 33-year-old patient had -hemolytic streptococcal sepsis. She had run a… 
22 Citations

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  • Medicine
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John F. Fulton, Coccidioidomycosis, and Penicillin

  • M. Tager
  • Medicine
    The Yale journal of biology and medicine
  • 1976
Penicillin was highly successful in the treatment of his other patient and soon of a second one with staphylococcal sepsis and pneumonia, which was the first clinical trial of penicillin under the control of the Office of Scientific Research and Development.


Excerpt In 1929, while examining plates seeded with staphylococci, Fleming1observed that colonies failed to grow in the neighborhood of a colony of a contaminating mold. Following up this chance ob...

Fulton and penicillin.

John Fulton, the late noted neurophysiologist, played a little known role in bringing penicillin to the world. He contributed behind-the-scenes support to Howard Florey and the penicillin research


The first use of penicillin in the United States.

The first use of penicillin in the United States.

Production of Penicillin in the United States (1941–1946)


The Pharmacological Basis of Therapeutics, by Prof. Louis Goodman and Prof. Alfred Gilman, New York: The Macmillan Company, 1941, p.

Located at: Medical Historical Library

    coccidioidomycosis, and penicillin

    • Yale J Biol Med
    • 1976