The First Pharmacoepidemiologic Investigations: national drug safety policy in the United States, 1901-1902

@article{Lilienfeld2008TheFP,
  title={The First Pharmacoepidemiologic Investigations: national drug safety policy in the United States, 1901-1902},
  author={D. Lilienfeld},
  journal={Perspectives in Biology and Medicine},
  year={2008},
  volume={51},
  pages={188 - 198}
}
  • D. Lilienfeld
  • Published 2008
  • Medicine
  • Perspectives in Biology and Medicine
The pharmaceutical industry developed in the late 19th century as a consequence of both scientific and commercial innovations, such as the development of diphtheria antitoxin and the commercialization of smallpox vaccine. Two tetanus outbreaks in 1901-from contaminated diphtheria antitoxin in St. Louis, Missouri, and contaminated smallpox vaccine in Camden, New Jersey-raised public concern about pharmaceutical safety. In St. Louis, errant manufacturing processes were found to be the source of… Expand
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