The Fatty Acid Transport Protein (FATP) Family: Very Long Chain Acyl-CoA Synthetases or Solute Carriers?

@article{Jia2007TheFA,
  title={The Fatty Acid Transport Protein (FATP) Family: Very Long Chain Acyl-CoA Synthetases or Solute Carriers?},
  author={Zhenzhen Jia and Zhengtong Pei and Dony A Maiguel and Cicely J. Toomer and Paul A. Watkins},
  journal={Journal of Molecular Neuroscience},
  year={2007},
  volume={33},
  pages={25-31}
}
Cellular fatty acids typically derive from uptake from the extracellular milieu and, to a lesser extent, de novo synthesis. Extracellular fatty acids must traverse the plasma membrane, after which they are activated to their CoA thioesters for subsequent metabolism. Both uptake and metabolism are rapid processes, and there has been considerable debate as to whether transport of fatty acids across the lipid bilayer of the plasma membrane proceeds by diffusion or requires transport proteins. One… CONTINUE READING

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