The Fate of L5-S1 With Low-Dose BMP-2 and Pelvic Fixation, With or Without Interbody Fusion, in Adult Deformity Surgery.

@article{Annis2015TheFO,
  title={The Fate of L5-S1 With Low-Dose BMP-2 and Pelvic Fixation, With or Without Interbody Fusion, in Adult Deformity Surgery.},
  author={Prokopis Annis and Darrel Scott Brodke and William Ryan Spiker and Michael David Daubs and Brandon D. Lawrence},
  journal={Spine},
  year={2015},
  volume={40 11},
  pages={E634-9}
}
STUDY DESIGN Retrospective comparative case series. OBJECTIVE Evaluate L5-S1 fusion rates when lower dose of bone morphogenic protein-2 (BMP-2) (average 3.2 mg) and pelvic fixation were used, with or without interbody fusion. SUMMARY OF BACKGROUND DATA Pseudarthrosis at L5-S1 is one of the most common complications of long fusions to the sacrum in adult deformity surgery. Strategies for decreasing pseudarthrosis include interbody fusion, use of BMP-2 at the lumbosacral junction, and the use… CONTINUE READING
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