The False-positive to False-negative Ratio in Epidemiologic Studies

@article{Ioannidis2011TheFT,
  title={The False-positive to False-negative Ratio in Epidemiologic Studies},
  author={J. Ioannidis and R. Tarone and J. Mclaughlin},
  journal={Epidemiology},
  year={2011},
  volume={22},
  pages={450-456}
}
The ratio of false-positive to false-negative findings (FP:FN ratio) is an informative metric that warrants further evaluation. The FP:FN ratio varies greatly across different epidemiologic areas. In genetic epidemiology, it has varied from very high values (possibly even >100:1) for associations reported in candidate-gene studies to very low values (1:100 or lower) for associations with genome-wide significance. The substantial reduction over time in the FP:FN ratio in human genome… Expand
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  • J. Ioannidis
  • Medicine, Computer Science
  • Statistics in medicine
  • 2016
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