The FGF2 gene in a myopia animal model and human subjects

@inproceedings{An2012TheFG,
  title={The FGF2 gene in a myopia animal model and human subjects},
  author={Jianhong An and Edward Hsi and Xiangtian Zhou and Yijin Tao and Suh-Hang H Juo and Chia Shan Liang},
  booktitle={Molecular vision},
  year={2012}
}
PURPOSE Fibroblast growth factor-2 (FGF2) has been implied in the development of myopia according to previous studies investigating FGF2 in the sclera and retinal pigment epithelium. This study measured retinal FGF2 gene expression in an animal model and also tested for the association between single nucleotide polymorphisms (SNPs) in FGF2 and high myopia. METHODS The guinea pigs were assigned to 2 groups: form deprivation myopia (FDM) for two weeks and normal control (free of form… CONTINUE READING

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