The Expression of p66Shc Protein in Benign, Premalignant, and Malignant Gastrointestinal Lesions

@article{Liu2014TheEO,
  title={The Expression of p66Shc Protein in Benign, Premalignant, and Malignant Gastrointestinal Lesions},
  author={Ganglei Liu and Biao Xie and Lin Gong and Jianping Zhou and Guoshun Shu},
  journal={Pathology & Oncology Research},
  year={2014},
  volume={20},
  pages={733-739}
}
ROS produced from Oxidative stress have long been recognized to be involved in carcinogenesis. p66Shc generates H2O2 by oxidizing cytochrome c, and its expression has been reported to be elevated in several tumors. However, the expression of p66Shc in gastric cancer has not been reported, and its role in colorectal cancer has not been well elucidated. This study investigated p66Shc expression in benign, premalignant, and malignant gastric and colorectal lesions. p66Shc expression in 146 gastric… CONTINUE READING
2 Citations
27 References
Similar Papers

References

Publications referenced by this paper.
Showing 1-10 of 27 references

Similar Papers

Loading similar papers…