The Expanding Landscape of Alternative Splicing Variation in Human Populations

@inproceedings{Park2018TheEL,
  title={The Expanding Landscape of Alternative Splicing Variation in Human Populations},
  author={Eddie Park and Zhicheng Pan and Zijun Zhang and Lan Lin and Yi Xing},
  booktitle={American journal of human genetics},
  year={2018}
}
Alternative splicing is a tightly regulated biological process by which the number of gene products for any given gene can be greatly expanded. Genomic variants in splicing regulatory sequences can disrupt splicing and cause disease. Recent developments in sequencing technologies and computational biology have allowed researchers to investigate alternative splicing at an unprecedented scale and resolution. Population-scale transcriptome studies have revealed many naturally occurring genetic… CONTINUE READING
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