The Ex Vivo Production of IL-6 and IL-21 by CD4+ T Cells is Directly Associated with Neurological Disability in Neuromyelitis Optica Patients

@article{Linhares2012TheEV,
  title={The Ex Vivo Production of IL-6 and IL-21 by CD4+ T Cells is Directly Associated with Neurological Disability in Neuromyelitis Optica Patients},
  author={Ulisses C. Linhares and Patr{\'i}cia Botelho Schiavoni and Priscila Oliveira Barros and Taissa M. Kasahara and Bruna Gomes Teixeira and Thais B. Ferreira and Regina MP Alvarenga and Joana Hygino and Morgana M. M. Vieira and Vera Carolina B. Bittencourt and Regis M. Andrade and Arnaldo Feitosa Braga de Andrade and Cleonice A M Bento},
  journal={Journal of Clinical Immunology},
  year={2012},
  volume={33},
  pages={179-189}
}
Neuromyelitis optica (NMO), also known as Devic’s disease, is an autoimmune, inflammatory disorder of the central nervous system (CNS) in which the immune system attacks myelin of the neurons located at the optic nerves and spinal cord, thus producing a simultaneous or sequential optic neuritis and myelitis. The objective of this study was evaluated the background T-cell function of patients suffering from neuromyelitis optica (NMO), an autoimmune disorder of the central nervous system. In our… CONTINUE READING

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