The Evolving Role of Taurolidine in Cancer Therapy

@article{Neary2009TheER,
  title={The Evolving Role of Taurolidine in Cancer Therapy},
  author={Peter M. Neary and Patrick Hallihan and Jiu Hua Wang and Rolf W. Pfirrmann and David J. Bouchier-Hayes and Henry Paul Redmond},
  journal={Annals of Surgical Oncology},
  year={2009},
  volume={17},
  pages={1135-1143}
}
Background and DesignTaurolidine consists of two taurinamide rings derived from the naturally occurring amino acid taurine. It has been utilized to prevent adhesions, as an antimicrobial, and as an anti-inflammatory agent. More recently, it has been found to exert antineoplastic activity. We reviewed the literature regarding taurolidine and its role in cancer treatment.Results and ConclusionTaurolidine induces cancer cell death through a variety of mechanisms. Even now, all the antineoplastic… CONTINUE READING

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