The Evolutionary Pathway of X Chromosome Inactivation in Mammals

  title={The Evolutionary Pathway of X Chromosome Inactivation in Mammals},
  author={A Iu Shevchenko and I G Zakharova and Suren M Zakian},
  booktitle={Acta naturae},
X chromosome inactivation is a complex process that occurs in marsupial and eutherian mammals. The process is thought to have arisen during the differentiation of mammalian sex chromosomes to achieve an equal dosage of X chromosome genes in males and females. The differences in the X chromosome inactivation processes in marsupial and eutherian mammals are considered, and the hypotheses on its origin and evolution are discussed in this review. 
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