The Evolution of the Differentiation-Specific Histone H1 Gene Basal Promoter

@article{Peretti1997TheEO,
  title={The Evolution of the Differentiation-Specific Histone H1 Gene Basal Promoter},
  author={Marie Peretti and Saadi Khochbin},
  journal={Journal of Molecular Evolution},
  year={1997},
  volume={44},
  pages={128-134}
}
The comparison of the rat H10 gene promoter sequence with that of known H10 genes showed a high evolutionary conservation of regulatory elements involved in the control of the basal transcription of the gene. This finding suggests that the regulation of H10 gene expression is also controlled by a very conserved mechanism within vertebrates. In order to confirm this hypothesis, we destroyed three major cis-acting elements in the H10 gene promoter by site-directed mutagenesis and showed that… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 11 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 54 references

Molecular basis of the activation of basal histone H 10 gene expression

  • S Khochbin, AP Wolffe
  • Nucleic Acids Res
  • 1993
Highly Influential
14 Excerpts

Comparison of the late H 1 histone genes of the sea urchin Lytechinus pictus and Strongylocentrotus purpu - ratus

  • JA Knowles, ZC Lai, G Childs
  • Nucleic Acids Res
  • 1987
Highly Influential
5 Excerpts

A H 1 histone

  • K Duncliffe, Rondahl HME, RE WellsJ
  • GENE
  • 1995
2 Excerpts

Similar Papers

Loading similar papers…