The Evolution of RecD Outside of the RecBCD Complex

  title={The Evolution of RecD Outside of the RecBCD Complex},
  author={Michael J. Montague and Christian H Barnes and Hamilton O. Smith and R Y Chuang and Sanjay Vashee},
  journal={Journal of Molecular Evolution},
The common understanding of the function of RecD, as derived predominantly from studies in Escherichia coli, is that RecD is one of three enzymes in the RecBCD double-stranded break repair DNA recombination complex. However, comparative genomics has revealed that many organisms possess a recD gene even though the other members of the complex, recB and recC, are not present. Further, bioinformatic analyses have shown that there is substantial sequence dissimilarity between recD genes associated… CONTINUE READING

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