• DOI:10.1086/303166
Corpus ID: 4398891

The Evolution of Mating Preferences and Major Histocompatibility Complex Genes

@article{Penn1999TheEO,
  title={The Evolution of Mating Preferences and Major Histocompatibility Complex Genes},
  author={D. Penn and W. Potts},
  journal={The American Naturalist},
  year={1999},
  volume={153},
  pages={145 - 164}
}

D. Penn, W. Potts

Published 1999

Biology, Medicine

The American Naturalist

House mice prefer mates genetically dissimilar at the major histocompatibility complex (MHC). The highly polymorphic MHC genes control immunological self/nonself recognition; therefore, this mating preference may function to provide “good genes” for an individual's offspring. However, the evidence for MHC‐dependent mating preferences is controversial, and its function remains unclear. Here we provide a critical review of the studies on MHC‐dependent mating preferences in mice, sheep, and humans… CONTINUE READING

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