The Evolution of Connectivity in Metabolic Networks

@article{Pfeiffer2005TheEO,
  title={The Evolution of Connectivity in Metabolic Networks},
  author={Thomas Pfeiffer and Orkun S. Soyer and Sebastian Bonhoeffer},
  journal={PLoS Biology},
  year={2005},
  volume={3},
  pages={651 - 654}
}
Processes in living cells are the result of interactions between biochemical compounds in highly complex biochemical networks. It is a major challenge in biology to understand causes and consequences of the specific design of these networks. A characteristic design feature of metabolic networks is the presence of hub metabolites such as ATP or NADH that are involved in a high number of reactions. To study the emergence of hub metabolites, we implemented computer simulations of a widely accepted… CONTINUE READING

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