The Evolution of Antiviral Defense Systems.

  title={The Evolution of Antiviral Defense Systems.},
  author={Benjamin R tenOever},
  journal={Cell host & microbe},
  volume={19 2},
Self-replicating genetic material presumably provided the architecture necessary for generating the last universal ancestor of all nucleic-acid-based life. As biological complexity increased in the billions of years that followed, the same genetic material also morphed into a wide spectrum of viruses and other parasitic genetic elements. The resulting struggle for existence drove the evolution of host defenses, giving rise to a perpetual arms race. This Perspective summarizes the antiviral… CONTINUE READING
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