The Ever-Changing Landscape of Rotavirus Serotypes

  title={The Ever-Changing Landscape of Rotavirus Serotypes},
  author={Miguel O'Ryan},
  journal={The Pediatric Infectious Disease Journal},
  • M. O'Ryan
  • Published 1 March 2009
  • Biology
  • The Pediatric Infectious Disease Journal
Rotavirus is a double-stranded RNA virus that is characterized by substantial genetic diversity. The various serotypes of rotavirus have been determined by the presence of neutralizing epitopes on the outer capsid of the protein shell. At present, 5 rotavirus serotypes (G1, G2, G3, G4, G9) are the predominant circulating strains, accounting for approximately 95% of strains worldwide, although there is considerable geographic variability. Incidence rates for various serotypes also vary… 
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