The Ets transcription factors of the PEA3 group: transcriptional regulators in metastasis.

@article{Launoit2006TheET,
  title={The Ets transcription factors of the PEA3 group: transcriptional regulators in metastasis.},
  author={Yvan de Launoit and J l Baert and Anne Chotteau-Leli{\`e}vre and Didier Mont{\'e} and Laurent Coutte and S{\'e}bastien Mauen and Virginie Firlej and Cindy Degerny and Kathye Verreman},
  journal={Biochimica et biophysica acta},
  year={2006},
  volume={1766 1},
  pages={79-87}
}
The PEA3 group is composed of three highly conserved Ets transcription factors: Erm, Er81, and Pea3. These proteins regulate transcription of multiple genes, and their transactivating potential is affected by post-translational modifications. Among their target genes are several matrix metalloproteases (MMPs), which are enzymes degrading the extracellular… CONTINUE READING